Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep954 | Steroid metabolism + action | ECE2016

First generation testosterone assays are influenced by sex hormone binding globulin concentrations as evidenced during oral contraceptive use and pregnancy

Heijboer Annemieke , Savelkoul Edo , Kruit Adrian , Endert Erik , Blankenstein Marinus

Introduction: The quality of testosterone assays has been a matter of debate for several years. Known limitations of testosterone immunoassays are the cross-reactivity with other steroids and a high variation in the low concentration range. We hypothesized that one of the additional limitations of testosterone immunoassays is an ineffective displacement of testosterone from its binding protein.Methods: Thirty samples from women not using oral contracepti...